Kratom Alkaloids

UPLC-DAD

High Level

Method Description

Kratom contains over 40 alkaloids, with mitragynine, paynantheine, speciociliatine, and speciogynine being the most abundant. These alkaloids are monitored because they determine the potency and potential effects of kratom products, which is critical for manufacturers establishing consistent dosing recommendations. The analysis targets the major alkaloids that typically comprise the majority of total alkaloid content and are responsible for kratom's primary pharmacological activity.

Analyte List

5
analytes
Analyte NameCAS #Type
Mitragynine4098-40-2Measured
Paynantheine4673-28-1Measured
Speciociliatine520-15-6Measured
Speciogynine4697-67-0Measured
Total Major AlkaloidsTotal (Sum)

Technical Data Sheet

Test Name (LIMS/CoA)
Kratom Alkaloids - High Level
Method Name
Determination of Kratom Alkaloid Content by UPLC-DAD
Method Code
ANA-TM-052
Platform Type
UPLC-DAD
Result Type
Quantitative – Panel
Reportable Unit
%, mg/g
Limit of Quantitation
Dynamic Reporting Limit: The reported LOD and LOQ
Acceptable Matrices
Dietary Supplements, Botanicals (Raw Materials, Extracts, Finished Products), API (Isolates, Active Ingredients)
*Prices and offerings are subject to change without notice.
Kratom Alkaloids
High Level
qPCR
Kratom Alkaloids
Test Code
ALKU
Status
Active
TaT
2–5 Business Days
Performing Lab
Cambium Analytica - In-House
Sample Needed
Beverages: 1 unit or 250 mL, whichever is more; All other matrices: 5 grams
Accreditation
ISO 17025
References
Cambium Analytica
Category
Botanical & Phytochemical
Subcategory
Phytochemicals - Quantitative Metabolites
Industries Available
Dietary Supplements

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