Residual Solvents Test



Turnaround Time:

2-3 Days


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Residual Solvents Test

Method Description

The Determination of Residual Solvents by Gas Chromatography-Mass Spectrometry with Headspace Sampling (GC-MS-HS) involves heating a sample to release volatile residues, which are then analyzed by GC-MS. This method ensures the detection and quantification of residual solvents in diverse matrices. GC-MS-HS provides high sensitivity and accuracy, making it essential in industries such as pharmaceuticals, ensuring compliance with safety standards and regulatory requirements. By efficiently identifying and quantifying residual solvents, this technique contributes to the quality control of products and ensures the safety of consumers.

Analyte List

Analyte Name LOD LOQ
1,2-Dichloroethane 0.061 ug/g 0.204 ug/g
2-Methylbutane 0.04 ug/g 0.135 ug/g
2-Methylpentane 0.046 ug/g 0.154 ug/g
2,2-Dimethylbutane 0.1 ug/g 0.335 ug/g
2,3-Dimethylbutane 0.088 ug/g 0.293 ug/g
3-Methylpentane 0.059 ug/g 0.195 ug/g
Acetone 1.57 ug/g 5.23 ug/g
Acetonitrile 1.85 ug/g 6.17 ug/g
Benzene 0.18 ug/g 0.59 ug/g
Butane 0.039 ug/g 0.131 ug/g
Butanes (Sum of Butane and Isobutane) N/A N/A
Chloroform 0.78 ug/g 2.59 ug/g
Ethanol 6.02 ug/g 20.1 ug/g
Ethyl Acetate 1.95 ug/g 6.49 ug/g
Ethyl Ether 1.37 ug/g 4.55 ug/g
Heptane 1.31 ug/g 4.37 ug/g
Hexane 1.42 ug/g 4.74 ug/g
Hexanes (Sum of Hexane, 2,2-Dimethylbutane, 2,3-Dimethylbutane, 2-Methylpentane, and 3-Methylpentane) N/A N/A
Isobutane 1.6 ug/g 5.34 ug/g
Isopropyl Alcohol 4.9 ug/g 16.3 ug/g
Methanol 7.89 ug/g 26.4 ug/g
Methylene Chloride 0.062 ug/g 0.205 ug/g
Neopentane 0.061 ug/g 0.202 ug/g
Pentane 1.46 ug/g 4.87 ug/g
Pentanes (Sum of Pentane, 2-Methylbutane, and Neopentane) N/A N/A
Propane 1.95 ug/g 6.51 ug/g
Toluene 1.88 ug/g 6.26 ug/g
Total Xylenes 2.02 ug/g 6.72 ug/g
Trichloroethylene 0.025 ug/g 0.084 ug/g

Technical Data Sheet

Test Name - Common
Residual Solvents Test
Method Name
Determination of Residual Solvents in Cannabis Extracts and Cannabis Infused Products by GCMS
Method Code
Headspace Gas Chromatography - Mass Spectrometry (GC-MS-HS)
Method Reference
Reportable Unit
Sample Size Requirements
Beverages: 1 unit or 250 mL, whichever is more; All other matrices: 5 grams
Available for
Cannabis & Hemp (Plant Materials, Extracts, Isolates, MIPs)
Additional Information
*Prices and offerings are subject to change without notice.