Lions Mane Metabolites: Memory Enhancing Effects

May 17, 2024

Lions Mane to enhance cognitive performance?

Journal of Neurochemistry’s study results demonstrate that NDPIH acts via a complementary neurotrophic pathway independent of TrkB with converging downstream ERK1/2 activation. Mice fed with H. erinaceus crude extract and hericene A also exhibited increased neurotrophin expression and downstream signaling, resulting in significantly enhanced hippocampal memory. Hericene A therefore acts through a novel pan-neurotrophic signaling pathway, leading to improved cognitive performance.

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A cognitively enhanced man with a Lions Man mushroom head