Lions Mane Metabolites: Memory Enhancing Effects
May 17, 2024
Lions Mane to enhance cognitive performance?
Journal of Neurochemistry’s study results demonstrate that NDPIH acts via a complementary neurotrophic pathway independent of TrkB with converging downstream ERK1/2 activation. Mice fed with H. erinaceus crude extract and hericene A also exhibited increased neurotrophin expression and downstream signaling, resulting in significantly enhanced hippocampal memory. Hericene A therefore acts through a novel pan-neurotrophic signaling pathway, leading to improved cognitive performance.
![A cognitively enhanced man with a Lions Man mushroom head](https://cdn.prod.website-files.com/6422f04f11e30d49c59d913a/6464e066074591457573de63_23XXXX-MI-MRK-musings-lions-mane-man.png)